Complications of diabetes
Both forms of diabetes ultimately lead to high blood sugar levels, a
condition called hyperglycemia. Over a long period of time, hyperglycemia
damages the retina of the eye, the kidneys, the nerves, and the blood vessels.
- Damage to the retina from diabetes (diabetic retinopathy) is a leading
cause of blindness.
- Damage to the kidneys from diabetes (diabetic nephropathy) is a leading
cause of kidney failure.
- Damage to the nerves from diabetes (diabetic neuropathy) is a leading
cause of foot wounds and ulcers, which frequently lead to foot and leg
amputations.
- Damage to the nerves in the autonomic nervous system can lead to
paralysis of the stomach (gastroparesis), chronic diarrhea, and an inability
to control heart rate and blood pressure with posture changes.
- Diabetes accelerates atherosclerosis, or the formation of fatty plaques
inside the arteries, which can lead to blockages or a clot (thrombus), which
can then lead to heart attack, stroke, and decreased circulation in the arms
and legs (peripheral vascular disease).
- Diabetes predisposes people to high blood pressure and high cholesterol
and triglyceride levels. These independently and together with hyperglycemia
increase the risk of heart disease, kidney disease, and other blood vessel
complications.
In the short run, diabetes can contribute to a number of acute (short-lived)
medical problems.
- Many infections are associated with diabetes, and infections are
frequently more dangerous in someone with diabetes because the body's normal
ability to fight infections is impaired. To compound the problem, infections
may worsen glucose control, which further delays recovery from infection.
- Hypoglycemia, or low blood sugar, occurs from time to time in most
people with diabetes. It results from taking too much diabetes medication or
insulin (sometimes called insulin reaction), missing a meal, doing more
exercise than usual, drinking too much alcohol, or taking certain
medications for other conditions. It is very important to recognize
hypoglycemia and be prepared to treat it at all times. Headache, feeling
dizzy, poor concentration, tremors of hands, and sweating are common
symptoms of hypoglycemia. You can faint or have a seizure if blood sugar
level gets too low.
- Diabetic ketoacidosis is a serious condition in which uncontrolled
hyperglycemia (usually due to complete lack of insulin or a relative
deficiency of insulin) over time creates a buildup in the blood of acidic
waste products called ketones. High levels of ketones can be very harmful.
This typically happens to people with type 1 diabetes who do not have good
blood glucose control. Diabetic ketoacidosis can be precipitated by
infection, stress, trauma, missing medications like insulin, or medical
emergencies like stroke and heart attack.
- Hyperosmolar hyperglycemic nonketotic syndrome is a serious condition in
which the blood sugar level gets very high. The body tries to get rid of the
excess blood sugar by eliminating it in the urine. This increases the amount
of urine significantly and often leads to dehydration so severe that it can
cause seizures, coma, even death. This syndrome typically occurs in people
with type 2 diabetes who are not controlling their blood sugar levels or
have become dehydrated or have stress, injury, stroke, or medications like
steroids.
http://www.emedicinehealth.com/diabetes/article_em.htm
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