10/26/07

Complications of diabetes

Complications of diabetes


Both forms of diabetes ultimately lead to high blood sugar levels, a
condition called hyperglycemia. Over a long period of time, hyperglycemia
damages the retina of the eye, the kidneys, the nerves, and the blood vessels.


  • Damage to the retina from diabetes (diabetic retinopathy) is a leading
    cause of blindness.



  • Damage to the kidneys from diabetes (diabetic nephropathy) is a leading
    cause of kidney failure.



  • Damage to the nerves from diabetes (diabetic neuropathy) is a leading
    cause of foot wounds and ulcers, which frequently lead to foot and leg
    amputations.



  • Damage to the nerves in the autonomic nervous system can lead to
    paralysis of the stomach (gastroparesis), chronic diarrhea, and an inability
    to control heart rate and blood pressure with posture changes.



  • Diabetes accelerates atherosclerosis, or the formation of fatty plaques
    inside the arteries, which can lead to blockages or a clot (thrombus), which
    can then lead to heart attack, stroke, and decreased circulation in the arms
    and legs (peripheral vascular disease).



  • Diabetes predisposes people to high blood pressure and high cholesterol
    and triglyceride levels. These independently and together with hyperglycemia
    increase the risk of heart disease, kidney disease, and other blood vessel
    complications.

In the short run, diabetes can contribute to a number of acute (short-lived)
medical problems.


  • Many infections are associated with diabetes, and infections are
    frequently more dangerous in someone with diabetes because the body's normal
    ability to fight infections is impaired. To compound the problem, infections
    may worsen glucose control, which further delays recovery from infection.



  • Hypoglycemia, or low blood sugar, occurs from time to time in most
    people with diabetes. It results from taking too much diabetes medication or
    insulin (sometimes called insulin reaction), missing a meal, doing more
    exercise than usual, drinking too much alcohol, or taking certain
    medications for other conditions. It is very important to recognize
    hypoglycemia and be prepared to treat it at all times. Headache, feeling
    dizzy, poor concentration, tremors of hands, and sweating are common
    symptoms of hypoglycemia. You can faint or have a seizure if blood sugar
    level gets too low.



  • Diabetic ketoacidosis is a serious condition in which uncontrolled
    hyperglycemia (usually due to complete lack of insulin or a relative
    deficiency of insulin) over time creates a buildup in the blood of acidic
    waste products called ketones. High levels of ketones can be very harmful.
    This typically happens to people with type 1 diabetes who do not have good
    blood glucose control. Diabetic ketoacidosis can be precipitated by
    infection, stress, trauma, missing medications like insulin, or medical
    emergencies like stroke and heart attack.



  • Hyperosmolar hyperglycemic nonketotic syndrome is a serious condition in
    which the blood sugar level gets very high. The body tries to get rid of the
    excess blood sugar by eliminating it in the urine. This increases the amount
    of urine significantly and often leads to dehydration so severe that it can
    cause seizures, coma, even death. This syndrome typically occurs in people
    with type 2 diabetes who are not controlling their blood sugar levels or
    have become dehydrated or have stress, injury, stroke, or medications like
    steroids.
    http://www.emedicinehealth.com/diabetes/article_em.htm



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